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Type 2 Diabetes Mellitus

 Read the full diabetes module for cardiology

Evidence-based drivers

Driver One
Reducing blood glucose levels and HbA1c levels reduces the risk of diabetic complications.  Intensive therapy has been shown to be superior to conventional therapy in terms of reducing glycemia and diabetic complications.

Driver Two
When monotherapy with an oral agent is no longer adequate, combination therapy with 2 or more oral agents has been shown to significantly improve glycemic control.

Driver Three
When oral monotherapy or combination oral therapy is no longer adequate, insulin can be added to the regimen to significantly improve glycemic control.

Driver Four
Benefits of insulin therapy, such as improved outcomes and glycemic control, outweigh risks such as the potential for inducing hypoglycemia.

Driver Five
Type 2 diabetes mellitus is a disease consisting of two components insulin resistance and insulin deficiency. 

This Scientific Evidence Based Medicine Module was funded by an educational grant from Sanofi-Aventis Pharmaceuticals Education Center.



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